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Which year to buy
Best betNo standoutNo year is clearly better than the rest
Newest we'd buy2024The latest year rated a good buy
Avoid2022Far more serious problems than usual
Be careful2021More problems; check the recalls were done
Bar height: serious owner complaints to NHTSA for that year per car on the road, against this model's usual year.
2014GOOD BUYSerious complaints 0.8× usual
16 serious complaints of 25, the most about steering (3) and suspension (2); per car on the road, 0.8× this model's usual year.
25 owner complaints · 0 recalls · EPA combined: 18–20 mpg · NHTSA: Not rated · 2014 trims and features
Every S-Class year's verdict →
Verdicts computed from NHTSA owner complaints, defect investigations and recalls. Cars on the road from New York State registrations. (How we judge.) Data checked 2026-10-06.
Trims and features
Engines: 4.7L 8-cyl turbo; 5.5L 8-cyl turbo · Drive: 4WD, RWD
2014 S-Class trims
| S550 | S550 4-MATIC | S63 AMG 4MATIC |
|---|
base price, seating and driver-assistance equipment from NHTSA's vehicle database (vPIC), as Mercedes-Benz reports it. Tech and comfort features (CarPlay, heated seats, sunroof) for Mercedes-Benz aren't in our data yet. "—": not verified in our sources. "Varies": standard on some versions of the trim.
Year by year
| Year | Engines | Drive | Fuel economy | Crash rating | Recalls | Owner complaints | Most-reported problem | CarPlay |
|---|---|---|---|---|---|---|---|---|
| 2024 | 3.0L 6-cyl turbo + supercharged, 362–443 hp 4.0L 8-cyl turbo, 496–604 hp 6.0L 12-cyl turbo, 621 hp | AWD | 15–24 mpg | Not rated | 0 | 6 | Electrical system (2) | — |
| 2023 | 3.0L 6-cyl, 362–429 hp 3.0L 6-cyl turbo, 362–429 hp 4.0L 8-cyl turbo, 496–603 hp 6.0L 12-cyl turbo, 621 hp | AWD | 14–23 mpg | Not rated | 0 | 12 | Forward collision avoidance (5) | — |
| 2022 | 3.0L 6-cyl, 362–429 hp 4.0L 8-cyl turbo, 463–603 hp 6.0L 12-cyl turbo, 621 hp | AWD | 15–24 mpg | Not rated | 0 | 48 | Forward collision avoidance (17) | — |
| 2021 | 3.0L 6-cyl, 362–429 hp 4.0L 8-cyl turbo, 463–603 hp | 4WD, RWD | 17–24 mpg | Not rated | 0 | 34 | Electrical system (10) | — |
| 2020 | 3.0L 6-cyl turbo, 362 hp 4.0L 8-cyl turbo, 463–603 hp 6.0L 12-cyl turbo, 621 hp | 4WD, RWD | 16–23 mpg | Not rated | 1 | 8 | Unknown or other (2) | — |
| 2019 | 3.0L 4-cyl turbo, 362 hp 3.0L 6-cyl turbo, 362 hp 4.0L 8-cyl turbo, 463–603 hp 6.0L 12-cyl turbo, 621 hp | 4WD, FWD, RWD | 16–23 mpg | Not rated | 1 | 18 | Unknown or other (5) | — |
| 2018 | 3.0L 6-cyl turbo, 362 hp 4.0L 8-cyl turbo, 463–603 hp 6.0L 12-cyl turbo, 621 hp | 4WD, FWD, RWD | 16–22 mpg | Not rated | 1 | 33 | Engine (7) | — |
| 2017 | 3.0L 6-cyl turbo 4.7L 8-cyl turbo, 449 hp 5.5L 8-cyl turbo, 577 hp 6.0L 12-cyl turbo, 621 hp | 4WD, RWD | 16–26 mpg | Not rated | 0 | 22 | Unknown or other (4) | — |
| 2016 | 3.0L 6-cyl turbo 4.7L 8-cyl turbo 5.5L 8-cyl turbo 6.0L 12-cyl turbo | 4WD, RWD | 15–26 mpg | Not rated | 0 | 29 | Unknown or other (13) | — |
| 2015 | 3.0L 6-cyl turbo 4.7L 8-cyl turbo 5.5L 8-cyl turbo 6.0L 12-cyl turbo | 4WD, RWD | 15–26 mpg | Not rated | 0 | 51 | Unknown or other (10) | — |
| 2014 | 4.7L 8-cyl turbo 5.5L 8-cyl turbo | 4WD, RWD | 18–20 mpg | Not rated | 0 | 25 | Unknown or other (5) | — |
| 2013 | 3.5L 6-cyl hybrid 4.7L 8-cyl turbo 5.5L 12-cyl turbo 5.5L 8-cyl turbo 6.0L 12-cyl turbo | 4WD, RWD | 14–21 mpg | Not rated | 0 | 9 | Electrical system (2) | — |
| 2012 | 3.5L 6-cyl hybrid 4.7L 8-cyl turbo 5.5L 12-cyl turbo 5.5L 8-cyl turbo 6.0L 12-cyl turbo | 4WD, RWD | 14–21 mpg | Not rated | 0 | 14 | Engine (7) | — |
| 2011 | 3.5L 6-cyl hybrid 5.5L 12-cyl turbo 5.5L 8-cyl 5.5L 8-cyl turbo 6.0L 12-cyl turbo | 4WD, RWD | 14–21 mpg | Not rated | 0 | 19 | Fuel/propulsion system (4) | — |
| 2010 | 3.5L 6-cyl hybrid 5.5L 12-cyl turbo 5.5L 8-cyl 6.0L 12-cyl turbo 6.3L 8-cyl | 4WD, RWD | 13–21 mpg | Not rated | 0 | 34 | Electrical system (10) | — |
Owner complaints are unverified reports to NHTSA, counted as filed: older years have had longer to collect them and sales aren't adjusted for, so see Which year to buy for a fair comparison. Most-reported problem: the component named in the most complaints that year. Sources: EPA, NHTSA, Apple.
Which years have…
Wireless Apple CarPlayApple CarPlay (wired or wireless)Wireless phone chargingHead-up displayPower liftgateLane centeringBlind-spot monitoringHeated front seatsVentilated (cooled) seatsHeated steering wheelLeather seatsRemote startSunroof or moonroofPanoramic roof
Every NHTSA-rated version: crash ratings, safety tech, recalls, complaints
| Year | Version | Stars | Forward collision warning | Lane departure warning | Recalls | Complaints |
|---|---|---|---|---|---|---|
| 2024 | Mercedes-Benz S-Class 4 DR AWD | Not Rated | Standard | Standard | 3 | 6 |
| 2024 | Mercedes-Benz S-Class 4 DR RWD | Not Rated | Standard | Standard | 3 | 6 |
| 2024 | Mercedes-Benz S-Class PHEV 4 DR AWD | Not Rated | Standard | Standard | 2 | 6 |
| 2023 | Mercedes-Benz Mercedes-Maybach S-Class 4 DR AWD | Not Rated | Standard | Standard | 9 | 11 |
| 2023 | Mercedes-Benz S-Class 4 DR AWD | Not Rated | Standard | Standard | 10 | 12 |
| 2023 | Mercedes-Benz S-Class Hybrid 4 DR AWD | Not Rated | Standard | Standard | 8 | 3 |
| 2022 | Mercedes-Benz Mercedes-Maybach S-Class 4 DR 4WD | Not Rated | Standard | No | 10 | 47 |
| 2022 | Mercedes-Benz S-Class 4 DR 4WD | Not Rated | Standard | No | 11 | 48 |
| 2022 | Mercedes-Benz S-Class 4 DR RWD | Not Rated | Standard | No | 11 | 48 |
| 2021 | Mercedes-Benz S-Class 2 DR RWD | Not Rated | Standard | No | 17 | 34 |
| 2021 | Mercedes-Benz S-Class 2 DR 4WD | Not Rated | Standard | No | 17 | 34 |
| 2021 | Mercedes-Benz S-Class 4 DR 4WD | Not Rated | No | No | 17 | 34 |
| 2021 | Mercedes-Benz S-Class Cabriolet C RWD | Not Rated | Standard | No | 17 | 34 |
| 2021 | Mercedes-Benz S-Class Cabriolet C 4WD | Not Rated | Standard | No | 17 | 34 |
| 2020 | Mercedes-Benz S-Class 2 DR 4WD | Not Rated | No | No | 7 | 7 |
| 2020 | Mercedes-Benz S-Class 4 DR 4WD | Not Rated | No | No | 7 | 7 |
| 2020 | Mercedes-Benz S-Class 2 DR RWD | Not Rated | No | No | 7 | 7 |
| 2020 | Mercedes-Benz S-Class 4 DR RWD | Not Rated | No | No | 7 | 7 |
| 2020 | Mercedes-Benz S-Class Cabriolet C 4WD | Not Rated | No | No | 7 | 7 |
| 2020 | Mercedes-Benz S-Class Cabriolet C RWD | Not Rated | No | No | 7 | 7 |
| 2020 | Mercedes-Benz S-Class Hybrid 4 DR RWD | Not Rated | No | No | 4 | 5 |
| 2019 | Mercedes-Benz S-Class 2 DR 4WD | Not Rated | Standard | Optional | 14 | 16 |
| 2019 | Mercedes-Benz S-Class 4 DR 4WD | Not Rated | Standard | Optional | 14 | 16 |
| 2019 | Mercedes-Benz S-Class 2 DR RWD | Not Rated | Standard | Optional | 14 | 16 |
| 2019 | Mercedes-Benz S-Class 4 DR RWD | Not Rated | Standard | Optional | 14 | 16 |
| 2019 | Mercedes-Benz S-Class Cabriolet C 4WD | Not Rated | Standard | Optional | 14 | 16 |
| 2019 | Mercedes-Benz S-Class Cabriolet C RWD | Not Rated | Standard | Optional | 14 | 16 |
| 2019 | Mercedes-Benz S560e 4 DR RWD | Not Rated | Standard | Optional | 10 | 9 |
| 2018 | Mercedes-Benz S-Class C RWD | Not Rated | Optional | Optional | 15 | 29 |
| 2018 | Mercedes-Benz S-Class C 4WD | Not Rated | Optional | Optional | 15 | 29 |
| 2018 | Mercedes-Benz S-Class 4 DR RWD | Not Rated | Standard | Optional | 15 | 29 |
| 2018 | Mercedes-Benz S-Class 4 DR 4WD | Not Rated | Standard | Optional | 15 | 29 |
| 2018 | Mercedes-Benz S-Class Coupe 2 DR 2WD | Not Rated | Optional | Optional | 15 | 29 |
| 2018 | Mercedes-Benz S-Class Coupe 2 DR 4WD | Not Rated | Optional | Optional | 15 | 29 |
| 2017 | Mercedes-Benz S-Class C RWD | Not Rated | Optional | Optional | 10 | 22 |
| 2017 | Mercedes-Benz S-Class C 4WD | Not Rated | Optional | Optional | 10 | 22 |
| 2017 | Mercedes-Benz S-Class 4 DR 4WD | Not Rated | Optional | Optional | 10 | 22 |
| 2017 | Mercedes-Benz S-Class 4 DR RWD | Not Rated | Optional | Optional | 10 | 22 |
| 2017 | Mercedes-Benz S-Class Hybrid 4 DR 4WD | Not Rated | Optional | Optional | 10 | 22 |
| 2017 | Mercedes-Benz S-Class Hybrid 4 DR RWD | Not Rated | Optional | Optional | 10 | 22 |
| 2016 | Mercedes-Benz S-Class 4 DR RWD | Not Rated | Optional | Optional | 7 | 29 |
| 2016 | Mercedes-Benz S-Class 4 DR 4WD | Not Rated | Optional | Optional | 7 | 29 |
| 2016 | Mercedes-Benz S-Class 2 DR FWD | Not Rated | Optional | Optional | 7 | 29 |
| 2016 | Mercedes-Benz S-Class 2 DR 4WD | Not Rated | Optional | Optional | 7 | 29 |
| 2016 | Mercedes-Benz S-Class Hybrid 4 DR RWD | Not Rated | Optional | Optional | 7 | 29 |
| 2016 | Mercedes-Benz S-Class Hybrid 4 DR 4WD | Not Rated | Optional | Optional | 7 | 29 |
| 2015 | Mercedes-Benz S-Class 4 DR RWD | Not Rated | Standard | Optional | 9 | 51 |
| 2015 | Mercedes-Benz S-Class 4 DR 4WD | Not Rated | Standard | Optional | 9 | 51 |
| 2015 | Mercedes-Benz S-Class Hybrid 4 DR RWD | Not Rated | Standard | Optional | 5 | 11 |
| 2015 | Mercedes-Benz S-Class Hybrid 4 DR 4WD | Not Rated | Standard | Optional | 5 | 11 |
| 2014 | Mercedes-Benz S-CLASS 4 DR 4WD | Not Rated | Standard | Optional | 6 | 25 |
| 2014 | Mercedes-Benz S-CLASS 4 DR RWD | Not Rated | Standard | Optional | 6 | 25 |
| 2013 | Mercedes-Benz S-Class 4 DR 4WD | Not Rated | Optional | Optional | 0 | 9 |
| 2013 | Mercedes-Benz S-Class 4 DR RWD | Not Rated | Optional | Optional | 0 | 9 |
| 2013 | Mercedes-Benz S-Class Hybrid 4 DR RWD | Not Rated | Optional | No | 0 | 9 |
| 2012 | Mercedes-Benz S-Class 4 DR AWD | Not Rated | Optional | Optional | 3 | 14 |
| 2012 | Mercedes-Benz S-Class 4 DR RWD | Not Rated | Optional | Optional | 3 | 14 |
| 2011 | Mercedes-Benz S-Class 4 DR RWD | Not Rated | No | No | 2 | 19 |
| 2010 | Mercedes-Benz S-Class 4-DR w/SAB | Not Rated | Optional | Optional | 0 | 34 |
Source: NHTSA.
Every EPA-rated version: engines and combined mpg
| Year | EPA model | Engines | Combined |
|---|---|---|---|
| 2024 | Maybach S680 4matic | Auto 9-spd, 12 cyl, 6.0 L, Turbo | 15 |
| 2024 | S500 4matic | Auto 9-spd, 6 cyl, 3.0 L, Turbo, Sup Charg | 24 |
| 2024 | S580 4matic | Auto 9-spd, 8 cyl, 4.0 L, Turbo | 21 |
| 2024 | S580 4matic Maybach | Auto 9-spd, 8 cyl, 4.0 L, Turbo | 21 |
| 2023 | Maybach S680 4matic | Auto 9-spd, 12 cyl, 6.0 L, Turbo | 14 |
| 2023 | S500 4matic | Auto 9-spd, 6 cyl, 3.0 L | 23 |
| 2023 | S580 4matic | Auto 9-spd, 8 cyl, 4.0 L, Turbo | 19 |
| 2023 | S580 4matic Maybach | Auto 9-spd, 8 cyl, 4.0 L, Turbo | 18 |
| 2023 | S580e 4matic | Auto 9-spd, 6 cyl, 3.0 L, Turbo | 23 |
| 2022 | Maybach S680 4matic | Auto 9-spd, 12 cyl, 6.0 L, Turbo | 15 |
| 2022 | S500 4matic | Auto 9-spd, 6 cyl, 3.0 L | 24 |
| 2022 | S580 4matic | Auto 9-spd, 8 cyl, 4.0 L, Turbo | 19 |
| 2022 | S580 4matic Maybach | Auto 9-spd, 8 cyl, 4.0 L, Turbo | 18 |
| 2021 | AMG S63 4matic Plus Convertible | Auto 9-spd, 8 cyl, 4.0 L, Turbo | 17 |
| 2021 | AMG S63 4matic Plus Coupe | Auto 9-spd, 8 cyl, 4.0 L, Turbo | 19 |
| 2021 | S500 4matic | Auto 9-spd, 6 cyl, 3.0 L | 24 |
| 2021 | S560 4matic Coupe | Auto 9-spd, 8 cyl, 4.0 L, Turbo | 20 |
| 2021 | S560 Convertible | Auto 9-spd, 8 cyl, 4.0 L, Turbo | 20 |
| 2021 | S580 4matic | Auto 9-spd, 8 cyl, 4.0 L, Turbo | 20 |
| 2021 | S580 4matic Maybach | Auto 9-spd, 8 cyl, 4.0 L, Turbo | 19 |
| 2020 | AMG S63 4matic Plus | Auto 9-spd, 8 cyl, 4.0 L, Turbo | 20 |
| 2020 | AMG S63 4matic Plus Convertible | Auto 9-spd, 8 cyl, 4.0 L, Turbo | 18 |
| 2020 | AMG S63 4matic Plus Coupe | Auto 9-spd, 8 cyl, 4.0 L, Turbo | 20 |
| 2020 | AMG S65 | Auto 7-spd, 12 cyl, 6.0 L, Turbo | 16 |
| 2020 | Maybach S650 | Auto 7-spd, 12 cyl, 6.0 L, Turbo | 16 |
| 2020 | S450 | Auto 9-spd, 6 cyl, 3.0 L, Turbo | 22 |
| 2020 | S450 4matic | Auto 9-spd, 6 cyl, 3.0 L, Turbo | 22 |
| 2020 | S560 | Auto 9-spd, 8 cyl, 4.0 L, Turbo | 21 |
| 2020 | S560 4matic | Auto 9-spd, 8 cyl, 4.0 L, Turbo | 21 |
| 2020 | S560 4matic Coupe | Auto 9-spd, 8 cyl, 4.0 L, Turbo | 20 |
| 2020 | S560 4matic Maybach | Auto 9-spd, 8 cyl, 4.0 L, Turbo | 19 |
| 2020 | S560 Convertible | Auto 9-spd, 8 cyl, 4.0 L, Turbo | 20 |
| 2020 | S560e | Auto 9-spd, 6 cyl, 3.0 L, Turbo | 23 |
| 2019 | AMG S63 4matic | Auto 9-spd, 8 cyl, 4.0 L, Turbo | 20 |
| 2019 | AMG S63 4matic Convertible | Auto 9-spd, 8 cyl, 4.0 L, Turbo | 18 |
| 2019 | AMG S63 4matic Coupe | Auto 9-spd, 8 cyl, 4.0 L, Turbo | 20 |
| 2019 | AMG S65 | Auto 7-spd, 12 cyl, 6.0 L, Turbo | 16 |
| 2019 | AMG S65 Convertible | Auto 7-spd, 12 cyl, 6.0 L, Turbo | 16 |
| 2019 | AMG S65 Coupe | Auto 7-spd, 12 cyl, 6.0 L, Turbo | 16 |
| 2019 | Maybach S560 4matic | Auto 9-spd, 8 cyl, 4.0 L, Turbo | 19 |
| 2019 | Maybach S650 | Auto 7-spd, 12 cyl, 6.0 L, Turbo | 16 |
| 2019 | S450 | Auto 9-spd, 6 cyl, 3.0 L, Turbo | 22 |
| 2019 | S450 4matic | Auto 9-spd, 6 cyl, 3.0 L, Turbo | 22 |
| 2019 | S560 | Auto 9-spd, 8 cyl, 4.0 L, Turbo | 21 |
| 2019 | S560 4matic | Auto 9-spd, 8 cyl, 4.0 L, Turbo | 21 |
| 2019 | S560 4matic Coupe | Auto 9-spd, 8 cyl, 4.0 L, Turbo | 20 |
| 2019 | S560 Convertible | Auto 9-spd, 8 cyl, 4.0 L, Turbo | 20 |
| 2019 | S560e | Auto 9-spd, 4 cyl, 3.0 L, Turbo | 23 |
| 2018 | AMG S63 4matic | Auto 9-spd, 8 cyl, 4.0 L, Turbo | 20 |
| 2018 | AMG S63 4matic Convertible | Auto 9-spd, 8 cyl, 4.0 L, Turbo | 18 |
| 2018 | AMG S63 4matic Coupe | Auto 9-spd, 8 cyl, 4.0 L, Turbo | 20 |
| 2018 | AMG S65 | Auto 7-spd, 12 cyl, 6.0 L, Turbo | 16 |
| 2018 | AMG S65 Convertible | Auto 7-spd, 12 cyl, 6.0 L, Turbo | 16 |
| 2018 | AMG S65 Coupe | Auto 7-spd, 12 cyl, 6.0 L, Turbo | 16 |
| 2018 | Maybach S560 4matic | Auto 9-spd, 8 cyl, 4.0 L, Turbo | 19 |
| 2018 | Maybach S650 | Auto 7-spd, 12 cyl, 6.0 L, Turbo | 16 |
| 2018 | S450 | Auto 9-spd, 6 cyl, 3.0 L, Turbo | 22 |
| 2018 | S450 4matic | Auto 9-spd, 6 cyl, 3.0 L, Turbo | 22 |
| 2018 | S560 | Auto 9-spd, 8 cyl, 4.0 L, Turbo | 21 |
| 2018 | S560 4matic | Auto 9-spd, 8 cyl, 4.0 L, Turbo | 21 |
| 2018 | S560 4matic Coupe | Auto 9-spd, 8 cyl, 4.0 L, Turbo | 21 |
| 2018 | S560 Convertible | Auto 9-spd, 8 cyl, 4.0 L, Turbo | 20 |
| 2017 | AMG S63 4matic | Auto 7-spd, 8 cyl, 5.5 L, Turbo | 18 |
| 2017 | AMG S63 4matic Convertible | Auto 7-spd, 8 cyl, 5.5 L, Turbo | 17 |
| 2017 | AMG S63 4matic Coupe | Auto 7-spd, 8 cyl, 5.5 L, Turbo | 18 |
| 2017 | AMG S65 | Auto 7-spd, 12 cyl, 6.0 L, Turbo | 16 |
| 2017 | Maybach S550 4matic | Auto 9-spd, 8 cyl, 4.7 L, Turbo | 19 |
| 2017 | Maybach S600 | Auto 7-spd, 12 cyl, 6.0 L, Turbo | 16 |
| 2017 | Maybach S650 Convertible | Auto 7-spd, 12 cyl, 6.0 L, Turbo | 16 |
| 2017 | S550 | Auto 9-spd, 8 cyl, 4.7 L, Turbo | 21 |
| 2017 | S550 4matic | Auto 9-spd, 8 cyl, 4.7 L, Turbo | 20 |
| 2017 | S550 4matic Coupe | Auto 9-spd, 8 cyl, 4.7 L, Turbo | 20 |
| 2017 | S550 Convertible | Auto 9-spd, 8 cyl, 4.7 L, Turbo | 20 |
| 2017 | S550e | Auto 7-spd, 6 cyl, 3.0 L, Turbo | 26 |
| 2017 | S600 | Auto 7-spd, 12 cyl, 6.0 L, Turbo | 16 |
| 2017 | S65 AMG Convertible | Auto 7-spd, 12 cyl, 6.0 L, Turbo | 16 |
| 2017 | S65 AMG Coupe | Auto 7-spd, 12 cyl, 6.0 L, Turbo | 16 |
| 2016 | AMG S63 4matic | Auto 7-spd, 8 cyl, 5.5 L, Turbo | 18 |
| 2016 | AMG S63 4matic Coupe | Auto 7-spd, 8 cyl, 5.5 L, Turbo | 18 |
| 2016 | AMG S65 | Auto 7-spd, 12 cyl, 6.0 L, Turbo | 15 |
| 2016 | AMG S65 Coupe | Auto 7-spd, 12 cyl, 6.0 L, Turbo | 15 |
| 2016 | Maybach S 600 | Auto 7-spd, 12 cyl, 6.0 L, Turbo | 15 |
| 2016 | S550 | Auto 7-spd, 8 cyl, 4.7 L, Turbo | 20 |
| 2016 | S550 4matic | Auto 7-spd, 8 cyl, 4.7 L, Turbo | 19 |
| 2016 | S550 4matic Coupe | Auto 7-spd, 8 cyl, 4.7 L, Turbo | 19 |
| 2016 | S550e | Auto 7-spd, 6 cyl, 3.0 L, Turbo | 26 |
| 2016 | S600 | Auto 7-spd, 12 cyl, 6.0 L, Turbo | 16 |
| 2015 | S550 | Auto 7-spd, 8 cyl, 4.7 L, Turbo | 20 |
| 2015 | S550 4matic | Auto 7-spd, 8 cyl, 4.7 L, Turbo | 19 |
| 2015 | S550 4matic Coupe | Auto 7-spd, 8 cyl, 4.7 L, Turbo | 19 |
| 2015 | S550e | Auto 7-spd, 6 cyl, 3.0 L, Turbo | 26 |
| 2015 | S600 | Auto 7-spd, 12 cyl, 6.0 L, Turbo | 16 |
| 2015 | S63 AMG 4matic | Auto 7-spd, 8 cyl, 5.5 L, Turbo | 18 |
| 2015 | S63 AMG 4matic Coupe | Auto 7-spd, 8 cyl, 5.5 L, Turbo | 18 |
| 2015 | S65 AMG | Auto 7-spd, 12 cyl, 6.0 L, Turbo | 15 |
| 2015 | S65 AMG Coupe | Auto 7-spd, 12 cyl, 6.0 L, Turbo | 15 |
| 2014 | S550 | Auto 7-spd, 8 cyl, 4.7 L, Turbo | 20 |
| 2014 | S550 4matic | Auto 7-spd, 8 cyl, 4.7 L, Turbo | 19 |
| 2014 | S63 AMG 4matic | Auto 7-spd, 8 cyl, 5.5 L, Turbo | 18 |
| 2013 | S400 Hybrid | Auto 7-spd, 6 cyl, 3.5 L | 21 |
| 2013 | S550 | Auto 7-spd, 8 cyl, 4.7 L, Turbo | 19 |
| 2013 | S550 4matic | Auto 7-spd, 8 cyl, 4.7 L, Turbo | 18 |
| 2013 | S600 | Auto 5-spd, 12 cyl, 5.5 L, Turbo | 14 |
| 2013 | S63 AMG | Auto 7-spd, 8 cyl, 5.5 L, Turbo | 18 |
| 2013 | S65 AMG | Auto 5-spd, 12 cyl, 6.0 L, Turbo | 15 |
| 2012 | S400 Hybrid | Auto 7-spd, 6 cyl, 3.5 L | 21 |
| 2012 | S550 | Auto 7-spd, 8 cyl, 4.7 L, Turbo | 19 |
| 2012 | S550 4matic | Auto 7-spd, 8 cyl, 4.7 L, Turbo | 18 |
| 2012 | S600 | Auto 5-spd, 12 cyl, 5.5 L, Turbo | 14 |
| 2012 | S63 AMG | Auto 7-spd, 8 cyl, 5.5 L, Turbo | 18 |
| 2012 | S65 AMG | Auto 5-spd, 12 cyl, 6.0 L, Turbo | 15 |
| 2011 | S400 Hybrid | Auto 7-spd, 6 cyl, 3.5 L | 21 |
| 2011 | S550 | Auto 7-spd, 8 cyl, 5.5 L | 18 |
| 2011 | S550 4matic | Auto 7-spd, 8 cyl, 5.5 L | 17 |
| 2011 | S600 | Auto 5-spd, 12 cyl, 5.5 L, Turbo | 14 |
| 2011 | S63 AMG | Auto 7-spd, 8 cyl, 5.5 L, Turbo | 18 |
| 2011 | S65 AMG | Auto 5-spd, 12 cyl, 6.0 L, Turbo | 14 |
| 2010 | S400 Hybrid | Auto 7-spd, 6 cyl, 3.5 L | 21 |
| 2010 | S550 | Auto 7-spd, 8 cyl, 5.5 L | 18 |
| 2010 | S550 4matic | Auto 7-spd, 8 cyl, 5.5 L | 17 |
| 2010 | S600 | Auto 5-spd, 12 cyl, 5.5 L, Turbo | 13 |
| 2010 | S63 AMG | Auto 7-spd, 8 cyl, 6.3 L | 14 |
| 2010 | S65 AMG | Auto 5-spd, 12 cyl, 6.0 L, Turbo | 13 |
Source: fueleconomy.gov.