Which year to buy
Best betNo standoutNo year is clearly better than the rest
Newest we'd buy2025The latest year rated a good buy
AvoidNoneNo year stands out as bad
Be careful2012, 2017, 2024More problems; check the recalls were done
Too new to judge: 2026. Give a new year a year or two of owner reports.
Bar height: serious owner complaints to NHTSA for that year per car on the road, against this model's usual year.
Verdicts computed from NHTSA owner complaints, defect investigations and recalls. Cars on the road from New York State registrations. (How we judge.) Data checked 2026-10-06.
Trims and features
2027 E-Class trims
| E350 | E350 4MATIC | E450 4MATIC | E450 4MATIC All-Terrain | |
|---|---|---|---|---|
| Apple CarPlay | Standard | Standard | Standard | Standard |
| Wireless Apple CarPlay | Standard | Standard | Standard | Standard |
| Android Auto | Standard | Standard | Standard | Standard |
| Wireless phone charging | Standard | Standard | Standard | Standard |
| Head-up display | Optional | Optional | Optional | Optional |
| Heated front seats | Standard | Standard | Standard | Standard |
| Ventilated front seats | Optional | Optional | Optional | Optional |
| Heated rear seats | Optional | Optional | Optional | Optional |
| Heated steering wheel | Optional | Optional | Optional | Optional |
| Leather seats | Optional | Optional | Optional | Optional |
| Remote start | Standard | Standard | Standard | Standard |
| Sunroof or moonroof | Standard | Standard | Standard | Standard |
| Panoramic roof | Standard | Standard | Standard | Standard |
| Power liftgate or tailgate | Standard | Standard | Standard | Standard |
| 360-degree camera | Standard | Standard | Standard | Standard |
| Blind-spot warning | Standard | Standard | Standard | Standard |
| Lane centering | Optional | Optional | Optional | Optional |
Features from Mercedes-Benz's 2027 equipment guide ("Optional": a package or option adds it); base price, seating and driver-assistance equipment from NHTSA's vehicle database (vPIC), as Mercedes-Benz reports it. "—": not verified in our sources. "Varies": standard on some versions of the trim.
Year by year
| Year | Engines | Drive | Fuel economy | Crash rating | Recalls | Owner complaints | Most-reported problem | CarPlay |
|---|---|---|---|---|---|---|---|---|
| 2026 | 2.0L 4-cyl turbo, 255 hp 3.0L 6-cyl turbo + supercharged, 375–443 hp 3.0L 6-cyl turbo hybrid, 375–443 hp | AWD, RWD | 22–28 mpg | Not rated | 0 | 6 | Electrical system (3) | — |
| 2025 | 2.0L 4-cyl turbo, 255 hp 3.0L 6-cyl turbo + supercharged, 375–577 hp 3.0L 6-cyl turbo hybrid, 375–577 hp | AWD, RWD | 23–28 mpg | — | 3 | 9 | Electrical system (6) | — |
| 2024 | 2.0L 4-cyl turbo, 255 hp 3.0L 6-cyl turbo + supercharged, 375 hp | AWD | 25–27 mpg | Not rated | 0 | 25 | Electrical system (12) | — |
| 2023 | 2.0L 4-cyl turbo, 255 hp 3.0L 6-cyl, 362–429 hp 3.0L 6-cyl turbo, 362–429 hp 4.0L 8-cyl turbo, 603 hp | AWD, RWD | 19–26 mpg | 5 of 5 | 0 | 24 | Engine (7) | — |
| 2022 | 2.0L 4-cyl turbo, 241–362 hp 3.0L 6-cyl, 329–429 hp 3.0L 6-cyl turbo, 329–429 hp | 4WD, AWD, RWD | 22–26 mpg | 5 of 5 | 0 | 22 | Electrical system (5) | — |
| 2021 | 2.0L 4-cyl turbo, 241–362 hp 3.0L 6-cyl, 329–396 hp 3.0L 6-cyl turbo, 329–396 hp 4.0L 8-cyl turbo | 4WD, RWD | 18–26 mpg | 5 of 5 | 15 | 25 | Electrical system (8) | — |
| 2020 | 2.0L 4-cyl turbo, 241–362 hp 3.0L 6-cyl, 329–429 hp 3.0L 6-cyl turbo, 329–429 hp 4.0L 8-cyl turbo, 603 hp | 4WD, RWD | 18–26 mpg | 5 of 5 | 1 | 24 | Engine (7) | — |
| 2019 | 2.0L 4-cyl turbo, 241–362 hp 3.0L 6-cyl, 329–603 hp 3.0L 6-cyl turbo, 329–603 hp 4.0L 8-cyl turbo, 603 hp | 4WD, RWD | 18–25 mpg | 5 of 5 | 1 | 59 | Electrical system (12) | — |
| 2018 | 2.0L 4-cyl turbo, 241 hp 3.0L 6-cyl turbo, 329–603 hp 4.0L 8-cyl turbo, 603 hp | 4WD, RWD | 18–25 mpg | 5 of 5 | 1 | 70 | Engine (14) | — |
| 2017 | 2.0L 4-cyl turbo, 241 hp 3.0L 6-cyl turbo, 329–396 hp 4.7L 8-cyl turbo, 402 hp | 4WD, RWD | 20–25 mpg | 5 of 5 | 0 | 167 | Engine (40) | — |
| 2016 | 3.0L 6-cyl turbo 3.5L 6-cyl 4.7L 8-cyl turbo 5.5L 8-cyl turbo | 4WD, RWD | 18–23 mpg | 4 of 5 | 0 | 89 | Air bags (30) | — |
| 2015 | 3.0L 6-cyl turbo 3.5L 6-cyl 3.5L 6-cyl hybrid 4.7L 8-cyl turbo 5.5L 8-cyl turbo | 4WD, RWD | 18–25 mpg | 4 of 5 | 0 | 57 | Air bags (13) | — |
| 2014 | 3.5L 6-cyl 3.5L 6-cyl hybrid 4.7L 8-cyl turbo 5.5L 8-cyl turbo | 4WD, RWD | 17–26 mpg | 4 of 5 | 0 | 304 | Air bags (58) | — |
| 2013 | 3.5L 6-cyl 3.5L 6-cyl hybrid 4.7L 8-cyl turbo 5.5L 8-cyl turbo | 4WD, RWD | 18–26 mpg | Not rated | 0 | 185 | Air bags (56) | — |
| 2012 | 3.5L 6-cyl 4.7L 8-cyl turbo 5.5L 8-cyl turbo | 4WD, RWD | 18–23 mpg | Not rated | 0 | 235 | Air bags (92) | — |
| 2011 | 3.5L 6-cyl 5.5L 8-cyl 6.2L 8-cyl | 4WD, RWD | 15–20 mpg | Not rated | 0 | 296 | Air bags (141) | — |
| 2010 | 3.5L 6-cyl 5.5L 8-cyl 6.3L 8-cyl | 4WD, RWD | 15–21 mpg | Not rated | 0 | 258 | Air bags (100) | — |
Owner complaints are unverified reports to NHTSA, counted as filed: older years have had longer to collect them and sales aren't adjusted for, so see Which year to buy for a fair comparison. Most-reported problem: the component named in the most complaints that year. Sources: EPA, NHTSA, Apple.
Which years have…
Wireless Apple CarPlayApple CarPlay (wired or wireless)Wireless phone chargingHead-up displayThird row (7+ seats)Power liftgateLane centeringBlind-spot monitoring360-degree cameraHeated front seatsHeated second-row seatsVentilated (cooled) seatsHeated steering wheelLeather seatsRemote startSunroof or moonroofPanoramic roof
Every NHTSA-rated version: crash ratings, safety tech, recalls, complaints
| Year | Version | Stars | Forward collision warning | Lane departure warning | Recalls | Complaints |
|---|---|---|---|---|---|---|
| 2026 | MERCEDES-BENZ E-CLASS 4 DR N/A AWD | Not Rated | No | No | 1 | 6 |
| 2026 | MERCEDES-BENZ E-CLASS 4 DR N/A RWD | Not Rated | No | No | 1 | 6 |
| 2026 | MERCEDES-BENZ E-CLASS PHEV 4 DR PHEV RWD | Not Rated | No | No | 0 | 0 |
| 2026 | MERCEDES-BENZ E-CLASS WAGON SW N/A AWD | Not Rated | No | No | 0 | 0 |
| 2026 | MERCEDES-BENZ E-CLASS WAGON PHEV SW PHEV AWD | Not Rated | No | No | 0 | 0 |
| 2024 | Mercedes-Benz E-Class 4 DR AWD | Not Rated | Standard | Optional | 6 | 25 |
| 2024 | Mercedes-Benz E-Class 4 DR RWD | Not Rated | Standard | Optional | 6 | 25 |
| 2024 | Mercedes-Benz E-Class Wagon SW AWD | Not Rated | Standard | Optional | 2 | 7 |
| 2023 | Mercedes-Benz E-Class 4 DR AWD | 5 | Standard | Standard | 3 | 24 |
| 2023 | Mercedes-Benz E-Class 4 DR RWD | 5 | Standard | Standard | 3 | 24 |
| 2023 | Mercedes-Benz E-Class Cabriolet C AWD | Not Rated | Standard | Standard | 3 | 24 |
| 2023 | Mercedes-Benz E-Class Cabriolet C RWD | Not Rated | Standard | Standard | 3 | 24 |
| 2023 | Mercedes-Benz E-Class Coupe 2 DR AWD | Not Rated | Standard | Standard | 3 | 24 |
| 2023 | Mercedes-Benz E-Class Coupe 2 DR RWD | Not Rated | Standard | Standard | 3 | 24 |
| 2023 | Mercedes-Benz E-Class station wagon SW AWD | 5 | Standard | Standard | 5 | 24 |
| 2022 | Mercedes-Benz E-Class 4 DR 4WD | 5 | Standard | No | 2 | 22 |
| 2022 | Mercedes-Benz E-Class 4 DR RWD | 5 | Standard | No | 2 | 22 |
| 2022 | Mercedes-Benz E-Class Cabriolet C 4WD | Not Rated | Standard | No | 2 | 22 |
| 2022 | Mercedes-Benz E-Class Cabriolet C RWD | Not Rated | Standard | No | 2 | 22 |
| 2022 | Mercedes-Benz E-Class Coupe 2 DR 4WD | Not Rated | Standard | No | 2 | 22 |
| 2022 | Mercedes-Benz E-Class Coupe 2 DR RWD | Not Rated | Standard | No | 2 | 22 |
| 2022 | Mercedes-Benz E-Class station wagon SW 4WD | 5 | Standard | No | 8 | 22 |
| 2022 | Mercedes-Benz E-Class station wagon SW RWD | 5 | Standard | No | 8 | 22 |
| 2021 | Mercedes-Benz E-Class 2DR RWD | Not Rated | Standard | No | 15 | 20 |
| 2021 | Mercedes-Benz E-Class SW RWD | 5 | Standard | No | 15 | 20 |
| 2021 | Mercedes-Benz E-Class 4 DR RWD | 5 | Standard | No | 15 | 20 |
| 2021 | Mercedes-Benz E-Class 2DR 4WD | Not Rated | Standard | No | 15 | 20 |
| 2021 | Mercedes-Benz E-Class SW 4WD | 5 | Standard | No | 15 | 20 |
| 2021 | Mercedes-Benz E-Class 4 DR 4WD | 5 | Standard | No | 15 | 20 |
| 2021 | Mercedes-Benz E-Class Cabriolet C RWD | Not Rated | Standard | No | 15 | 20 |
| 2021 | Mercedes-Benz E-Class Cabriolet C 4WD | Not Rated | Standard | No | 15 | 20 |
| 2020 | Mercedes-Benz E-Class 2 DR 4WD | Not Rated | No | No | 15 | 21 |
| 2020 | Mercedes-Benz E-Class 4 DR 4WD | 5 | No | No | 15 | 21 |
| 2020 | Mercedes-Benz E-Class 2 DR RWD | Not Rated | No | No | 15 | 21 |
| 2020 | Mercedes-Benz E-Class 4 DR RWD | 5 | No | No | 15 | 21 |
| 2020 | Mercedes-Benz E-Class Cabriolet C 4WD | Not Rated | No | No | 15 | 21 |
| 2020 | Mercedes-Benz E-Class Cabriolet C RWD | Not Rated | No | No | 15 | 21 |
| 2020 | Mercedes-Benz E-Class station wagon SW 4WD | 5 | No | No | 11 | 18 |
| 2020 | Mercedes-Benz E-Class station wagon SW RWD | 5 | No | No | 11 | 18 |
| 2019 | Mercedes-Benz E-Class SW 4WD | 5 | Standard | Optional | 21 | 54 |
| 2019 | Mercedes-Benz E-Class 4 DR 4WD | 5 | Standard | Optional | 21 | 54 |
| 2019 | Mercedes-Benz E-Class SW RWD | 5 | Standard | Optional | 21 | 54 |
| 2019 | Mercedes-Benz E-Class 4 DR RWD | 5 | Standard | Optional | 21 | 54 |
| 2019 | Mercedes-Benz E-Class 2 DR 4WD | Not Rated | Standard | Optional | 21 | 54 |
| 2019 | Mercedes-Benz E-Class 2 DR RWD | Not Rated | Standard | Optional | 21 | 54 |
| 2019 | Mercedes-Benz E-Class Cabriolet C 4WD | Not Rated | Standard | Optional | 21 | 54 |
| 2019 | Mercedes-Benz E-Class Cabriolet C RWD | Not Rated | Standard | Optional | 21 | 54 |
| 2018 | Mercedes-Benz E-Class C RWD | Not Rated | Standard | Optional | 18 | 68 |
| 2018 | Mercedes-Benz E-Class C 4WD | Not Rated | Standard | Optional | 18 | 68 |
| 2018 | Mercedes-Benz E-Class 4 DR 4WD | 5 | Standard | Optional | 18 | 68 |
| 2018 | Mercedes-Benz E-Class 4 DR RWD | 5 | Standard | Optional | 18 | 68 |
| 2018 | Mercedes-Benz E-CLASS SW 4WD | 5 | Standard | Optional | 18 | 68 |
| 2018 | Mercedes-Benz E-CLASS SW RWD | 5 | Standard | Optional | 18 | 68 |
| 2018 | Mercedes-Benz E-Class 2 DR RWD | Not Rated | Standard | Optional | 18 | 68 |
| 2018 | Mercedes-Benz E-Class 2 DR 4WD | Not Rated | Standard | Optional | 18 | 68 |
| 2017 | Mercedes-Benz E-Class C 4WD | Not Rated | Optional | Optional | 20 | 167 |
| 2017 | Mercedes-Benz E-Class C RWD | Not Rated | Optional | Optional | 20 | 167 |
| 2017 | Mercedes-Benz E-CLASS SW 4WD | 5 | Standard | Optional | 20 | 167 |
| 2017 | Mercedes-Benz E-CLASS SW RWD | 5 | Standard | Optional | 20 | 167 |
| 2017 | Mercedes-Benz E-Class 4 DR RWD | 5 | Standard | Optional | 20 | 167 |
| 2017 | Mercedes-Benz E-Class 4 DR 4WD | 5 | Standard | Optional | 20 | 167 |
| 2017 | Mercedes-Benz E-Class 2 DR RWD | Not Rated | Optional | Optional | 20 | 167 |
| 2017 | Mercedes-Benz E-Class 2 DR 4WD | Not Rated | Optional | Optional | 20 | 167 |
| 2016 | Mercedes-Benz E-Class 2 DR 4WD | Not Rated | Optional | Optional | 9 | 89 |
| 2016 | Mercedes-Benz E-Class 2 DR RWD | Not Rated | Optional | Optional | 9 | 89 |
| 2016 | Mercedes-Benz E-CLASS SW RWD | 4 | Optional | Optional | 9 | 89 |
| 2016 | Mercedes-Benz E-CLASS SW 4WD | 4 | Optional | Optional | 9 | 89 |
| 2016 | Mercedes-Benz E-Class 4 DR RWD | 4 | Optional | Optional | 9 | 89 |
| 2016 | Mercedes-Benz E-Class 4 DR 4WD | 4 | Optional | Optional | 9 | 89 |
| 2016 | Mercedes-Benz E-Class Cabrio 2 DR RWD | Not Rated | Optional | Optional | 9 | 89 |
| 2016 | Mercedes-Benz E-Class Cabrio 2 DR 4WD | Not Rated | Optional | Optional | 9 | 89 |
| 2015 | Mercedes-Benz E-Class 2 DR RWD | Not Rated | Standard | Optional | 10 | 57 |
| 2015 | Mercedes-Benz E-Class 2 DR 4WD | Not Rated | Standard | Optional | 10 | 57 |
| 2015 | Mercedes-Benz E-CLASS SW 4WD | 4 | Standard | Optional | 10 | 57 |
| 2015 | Mercedes-Benz E-CLASS SW RWD | 4 | Standard | Optional | 10 | 57 |
| 2015 | Mercedes-Benz E-Class 4 DR 4WD | 4 | Standard | Optional | 10 | 57 |
| 2015 | Mercedes-Benz E-Class 4 DR RWD | 4 | Standard | Optional | 10 | 57 |
| 2015 | Mercedes-Benz E-Class Cabrio 2 DR RWD | Not Rated | Standard | Optional | 10 | 57 |
| 2015 | Mercedes-Benz E-Class Cabrio 2 DR 4WD | Not Rated | Standard | Optional | 10 | 57 |
| 2015 | Mercedes-Benz E-Class Hybrid 4 DR RWD | 4 | Optional | Optional | 10 | 57 |
| 2014 | Mercedes-Benz E-CLASS SW 4WD | 4 | Standard | Optional | 9 | 304 |
| 2014 | Mercedes-Benz E-CLASS SW RWD | 4 | Standard | Optional | 9 | 304 |
| 2014 | Mercedes-Benz E-CLASS 2 DR 4WD | Not Rated | Standard | Optional | 9 | 304 |
| 2014 | Mercedes-Benz E-CLASS 2 DR RWD | Not Rated | Standard | Optional | 9 | 304 |
| 2014 | Mercedes-Benz E-Class 4 DR AWD | 4 | Standard | Optional | 9 | 304 |
| 2014 | Mercedes-Benz E-Class 4 DR RWD | 4 | Standard | Optional | 9 | 304 |
| 2014 | Mercedes-Benz E-CLASS C RWD | Not Rated | Standard | Optional | 9 | 304 |
| 2014 | Mercedes-Benz E-Class Hybrid 4 DR RWD | 4 | No | No | 9 | 304 |
| 2013 | Mercedes-Benz E-Class 2 DR 4WD | Not Rated | Optional | Optional | 7 | 185 |
| 2013 | Mercedes-Benz E-Class 2 DR RWD | Not Rated | Optional | Optional | 7 | 185 |
| 2013 | Mercedes-Benz E-Class 4 DR AWD | Not Rated | Optional | Optional | 7 | 185 |
| 2013 | Mercedes-Benz E-Class 4 DR RWD | Not Rated | Optional | Optional | 7 | 185 |
| 2013 | Mercedes-Benz E-Class Cabriolet C RWD | Not Rated | Optional | Optional | 7 | 185 |
| 2013 | Mercedes-Benz E-Class Hybrid 4 DR AWD | Not Rated | Optional | No | 7 | 185 |
| 2013 | Mercedes-Benz E-Class Hybrid 4 DR RWD | Not Rated | Optional | No | 7 | 185 |
| 2013 | Mercedes-Benz E-Class Wagon SW 4WD | Not Rated | Optional | No | 7 | 185 |
| 2013 | Mercedes-Benz E-Class Wagon SW RWD | Not Rated | Optional | No | 7 | 185 |
| 2012 | Mercedes-Benz E-Class 4 DR AWD | Not Rated | Optional | Optional | 7 | 235 |
| 2012 | Mercedes-Benz E-Class 2 DR AWD | Not Rated | Optional | Optional | 7 | 235 |
| 2012 | Mercedes-Benz E-Class 4 DR RWD | Not Rated | Optional | Optional | 7 | 235 |
| 2012 | Mercedes-Benz E-Class 2 DR RWD | Not Rated | Optional | Optional | 7 | 235 |
| 2012 | Mercedes-Benz E-Class Cabriolet 2 DR RWD | Not Rated | Optional | Optional | 7 | 235 |
| 2011 | Mercedes-Benz E-Class 4 DR AWD | Not Rated | No | No | 9 | 296 |
| 2011 | Mercedes-Benz E-Class 2 DR AWD | Not Rated | No | No | 9 | 296 |
| 2011 | Mercedes-Benz E-Class 4 DR RWD | Not Rated | No | No | 9 | 296 |
| 2011 | Mercedes-Benz E-Class 2 DR RWD | Not Rated | No | No | 9 | 296 |
| 2011 | Mercedes-Benz E-Class Cabriolet 2 DR AWD | Not Rated | No | No | 9 | 296 |
| 2011 | Mercedes-Benz E-Class Cabriolet 2 DR RWD | Not Rated | No | No | 9 | 296 |
| 2010 | Mercedes-Benz E-Class 2-DR. w/SAB | Not Rated | Optional | Optional | 6 | 258 |
| 2010 | Mercedes-Benz E-Class 4-DR. w/SAB | Not Rated | Optional | Optional | 6 | 258 |
Source: NHTSA.
Every EPA-rated version: engines and combined mpg
| Year | EPA model | Engines | Combined |
|---|---|---|---|
| 2026 | AMG E53 Hybrid 4matic Plus | Auto 9-spd, 6 cyl, 3.0 L, Turbo | 24 |
| 2026 | AMG E53 Hybrid 4matic Plus (station wagon) | Auto 9-spd, 6 cyl, 3.0 L, Turbo | 22 |
| 2026 | E350 | Auto 9-spd, 4 cyl, 2.0 L, Turbo | 28 |
| 2026 | E350 4matic | Auto 9-spd, 4 cyl, 2.0 L, Turbo | 27 |
| 2026 | E450 4matic | Auto 9-spd, 6 cyl, 3.0 L, Turbo, Sup Charg | 25 |
| 2026 | E450 4matic All-Terrain (wagon) | Auto 9-spd, 6 cyl, 3.0 L, Turbo, Sup Charg | 25 |
| 2025 | AMG E53 Hybrid 4matic Plus | Auto 9-spd, 6 cyl, 3.0 L, Turbo | 23 |
| 2025 | E350 | Auto 9-spd, 4 cyl, 2.0 L, Turbo | 28 |
| 2025 | E350 4matic | Auto 9-spd, 4 cyl, 2.0 L, Turbo | 27 |
| 2025 | E450 4matic | Auto 9-spd, 6 cyl, 3.0 L, Turbo, Sup Charg | 25 |
| 2025 | E450 4matic All-Terrain (wagon) | Auto 9-spd, 6 cyl, 3.0 L, Turbo, Sup Charg | 25 |
| 2024 | E350 4matic | Auto 9-spd, 4 cyl, 2.0 L, Turbo | 27 |
| 2024 | E450 4matic | Auto 9-spd, 6 cyl, 3.0 L, Turbo, Sup Charg | 25 |
| 2024 | E450 4matic All-Terrain (wagon) | Auto 9-spd, 6 cyl, 3.0 L, Turbo, Sup Charg | 25 |
| 2023 | AMG E53 4matic Plus | Auto 9-spd, 6 cyl, 3.0 L | 24 |
| 2023 | AMG E53 4matic Plus Convertible | Auto 9-spd, 6 cyl, 3.0 L | 23 |
| 2023 | AMG E53 4matic Plus Coupe | Auto 9-spd, 6 cyl, 3.0 L | 23 |
| 2023 | AMG E63 S 4matic Plus | Auto 9-spd, 8 cyl, 4.0 L, Turbo | 19 |
| 2023 | AMG E63 S 4matic Plus (SW) | Auto 9-spd, 8 cyl, 4.0 L, Turbo | 19 |
| 2023 | E350 | Auto 9-spd, 4 cyl, 2.0 L, Turbo | 26 |
| 2023 | E350 4matic | Auto 9-spd, 4 cyl, 2.0 L, Turbo | 24 |
| 2023 | E450 4matic | Auto 9-spd, 6 cyl, 3.0 L, Turbo | 26 |
| 2023 | E450 4matic All-Terrain (wagon) | Auto 9-spd, 6 cyl, 3.0 L, Turbo | 24 |
| 2023 | E450 4matic Convertible | Auto 9-spd, 6 cyl, 3.0 L, Turbo | 24 |
| 2023 | E450 4matic Coupe | Auto 9-spd, 6 cyl, 3.0 L, Turbo | 24 |
| 2023 | E450 Convertible | Auto 9-spd, 6 cyl, 3.0 L, Turbo | 25 |
| 2023 | E450 Coupe | Auto 9-spd, 6 cyl, 3.0 L, Turbo | 25 |
| 2022 | AMG E53 4matic Plus | Auto 9-spd, 6 cyl, 3.0 L | 24 |
| 2022 | AMG E53 4matic Plus Convertible | Auto 9-spd, 6 cyl, 3.0 L | 22 |
| 2022 | AMG E53 4matic Plus Coupe | Auto 9-spd, 6 cyl, 3.0 L | 23 |
| 2022 | E350 | Auto 9-spd, 4 cyl, 2.0 L, Turbo | 26 |
| 2022 | E350 4matic | Auto 9-spd, 4 cyl, 2.0 L, Turbo | 24 |
| 2022 | E450 4matic | Auto 9-spd, 6 cyl, 3.0 L, Turbo | 25 |
| 2022 | E450 4matic All-Terrain (wagon) | Auto 9-spd, 6 cyl, 3.0 L, Turbo | 24 |
| 2022 | E450 4matic Convertible | Auto 9-spd, 6 cyl, 3.0 L, Turbo | 24 |
| 2022 | E450 4matic Coupe | Auto 9-spd, 6 cyl, 3.0 L, Turbo | 24 |
| 2022 | E450 Convertible | Auto 9-spd, 6 cyl, 3.0 L, Turbo | 25 |
| 2022 | E450 Coupe | Auto 9-spd, 6 cyl, 3.0 L, Turbo | 25 |
| 2021 | AMG E53 4matic Plus | Auto 9-spd, 6 cyl, 3.0 L | 25 |
| 2021 | AMG E53 4matic Plus Convertible | Auto 9-spd, 6 cyl, 3.0 L | 23 |
| 2021 | AMG E53 4matic Plus Coupe | Auto 9-spd, 6 cyl, 3.0 L | 24 |
| 2021 | AMG E63 S 4matic Plus | Auto 9-spd, 8 cyl, 4.0 L, Turbo | 18 |
| 2021 | AMG E63 S 4matic Plus (SW) | Auto 9-spd, 8 cyl, 4.0 L, Turbo | 18 |
| 2021 | E350 | Auto 9-spd, 4 cyl, 2.0 L, Turbo | 25 |
| 2021 | E350 4matic | Auto 9-spd, 4 cyl, 2.0 L, Turbo | 25 |
| 2021 | E450 4matic | Auto 9-spd, 6 cyl, 3.0 L, Turbo | 26 |
| 2021 | E450 4matic All-Terrain (wagon) | Auto 9-spd, 6 cyl, 3.0 L, Turbo | 24 |
| 2021 | E450 4matic Convertible | Auto 9-spd, 6 cyl, 3.0 L, Turbo | 25 |
| 2021 | E450 4matic Coupe | Auto 9-spd, 6 cyl, 3.0 L, Turbo | 25 |
| 2021 | E450 Convertible | Auto 9-spd, 6 cyl, 3.0 L, Turbo | 25 |
| 2021 | E450 Coupe | Auto 9-spd, 6 cyl, 3.0 L, Turbo | 26 |
| 2020 | AMG E53 4matic Plus | Auto 9-spd, 6 cyl, 3.0 L | 24 |
| 2020 | AMG E53 4matic Plus Convertible | Auto 9-spd, 6 cyl, 3.0 L | 23 |
| 2020 | AMG E53 4matic Plus Coupe | Auto 9-spd, 6 cyl, 3.0 L | 23 |
| 2020 | AMG E63 S 4matic Plus | Auto 9-spd, 8 cyl, 4.0 L, Turbo | 18 |
| 2020 | AMG E63 S 4matic Plus (wagon) | Auto 9-spd, 8 cyl, 4.0 L, Turbo | 19 |
| 2020 | E350 | Auto 9-spd, 4 cyl, 2.0 L, Turbo | 26 |
| 2020 | E350 4matic | Auto 9-spd, 4 cyl, 2.0 L, Turbo | 25 |
| 2020 | E450 4matic | Auto 9-spd, 6 cyl, 3.0 L, Turbo | 23 |
| 2020 | E450 4matic (station wagon) | Auto 9-spd, 6 cyl, 3.0 L, Turbo | 22 |
| 2020 | E450 4matic Convertible | Auto 9-spd, 6 cyl, 3.0 L, Turbo | 22 |
| 2020 | E450 4matic Coupe | Auto 9-spd, 6 cyl, 3.0 L, Turbo | 22 |
| 2020 | E450 Convertible | Auto 9-spd, 6 cyl, 3.0 L, Turbo | 23 |
| 2020 | E450 Coupe | Auto 9-spd, 6 cyl, 3.0 L, Turbo | 23 |
| 2019 | AMG E53 4matic Plus | Auto 9-spd, 6 cyl, 3.0 L | 24 |
| 2019 | AMG E53 4matic Plus Convertible | Auto 9-spd, 6 cyl, 3.0 L | 23 |
| 2019 | AMG E53 4matic Plus Coupe | Auto 9-spd, 6 cyl, 3.0 L | 23 |
| 2019 | AMG E63 S 4matic | Auto 9-spd, 8 cyl, 4.0 L, Turbo | 18 |
| 2019 | AMG E63 S 4matic (wagon) | Auto 9-spd, 8 cyl, 4.0 L, Turbo | 19 |
| 2019 | E300 | Auto 9-spd, 4 cyl, 2.0 L, Turbo | 25 |
| 2019 | E300 4matic | Auto 9-spd, 4 cyl, 2.0 L, Turbo | 24 |
| 2019 | E450 4matic | Auto 9-spd, 6 cyl, 3.0 L, Turbo | 23 |
| 2019 | E450 4matic (station wagon) | Auto 9-spd, 6 cyl, 3.0 L, Turbo | 22 |
| 2019 | E450 4matic Convertible | Auto 9-spd, 6 cyl, 3.0 L, Turbo | 22 |
| 2019 | E450 4matic Coupe | Auto 9-spd, 6 cyl, 3.0 L, Turbo | 22 |
| 2019 | E450 Convertible | Auto 9-spd, 6 cyl, 3.0 L, Turbo | 23 |
| 2019 | E450 Coupe | Auto 9-spd, 6 cyl, 3.0 L, Turbo | 23 |
| 2018 | AMG E43 4matic | Auto 9-spd, 6 cyl, 3.0 L, Turbo | 21 |
| 2018 | AMG E63 S 4matic | Auto 9-spd, 8 cyl, 4.0 L, Turbo | 18 |
| 2018 | AMG E63 S 4matic (wagon) | Auto 9-spd, 8 cyl, 4.0 L, Turbo | 18 |
| 2018 | E300 | Auto 9-spd, 4 cyl, 2.0 L, Turbo | 25 |
| 2018 | E300 4matic | Auto 9-spd, 4 cyl, 2.0 L, Turbo | 24 |
| 2018 | E400 4matic | Auto 9-spd, 6 cyl, 3.0 L, Turbo | 23 |
| 2018 | E400 4matic (station wagon) | Auto 9-spd, 6 cyl, 3.0 L, Turbo | 21 |
| 2018 | E400 4matic Convertible | Auto 9-spd, 6 cyl, 3.0 L, Turbo | 22 |
| 2018 | E400 4matic Coupe | Auto 9-spd, 6 cyl, 3.0 L, Turbo | 22 |
| 2018 | E400 Convertible | Auto 9-spd, 6 cyl, 3.0 L, Turbo | 22 |
| 2018 | E400 Coupe | Auto 9-spd, 6 cyl, 3.0 L, Turbo | 22 |
| 2017 | AMG E43 4matic | Auto 9-spd, 6 cyl, 3.0 L, Turbo | 21 |
| 2017 | E300 | Auto 9-spd, 4 cyl, 2.0 L, Turbo | 25 |
| 2017 | E300 4matic | Auto 9-spd, 4 cyl, 2.0 L, Turbo | 24 |
| 2017 | E400 4matic (station wagon) | Auto 9-spd, 6 cyl, 3.0 L, Turbo | 21 |
| 2017 | E400 4matic Coupe | Auto 7-spd, 6 cyl, 3.0 L, Turbo | 23 |
| 2017 | E400 Convertible | Auto 7-spd, 6 cyl, 3.0 L, Turbo | 23 |
| 2017 | E400 Coupe | Auto 7-spd, 6 cyl, 3.0 L, Turbo | 23 |
| 2017 | E550 Convertible | Auto 7-spd, 8 cyl, 4.7 L, Turbo | 20 |
| 2017 | E550 Coupe | Auto 7-spd, 8 cyl, 4.7 L, Turbo | 21 |
| 2016 | AMG E63 4matic | Auto 7-spd, 8 cyl, 5.5 L, Turbo | 19 |
| 2016 | AMG E63 S 4matic | Auto 7-spd, 8 cyl, 5.5 L, Turbo | 18 |
| 2016 | AMG E63 S 4matic (wagon) | Auto 7-spd, 8 cyl, 5.5 L, Turbo | 18 |
| 2016 | E350 | Auto 7-spd, 6 cyl, 3.5 L, SIDI; FFV Auto 7-spd, 6 cyl, 3.5 L, SIDI |
23 |
| 2016 | E350 4matic | Auto 7-spd, 6 cyl, 3.5 L, SIDI; FFV Auto 7-spd, 6 cyl, 3.5 L, SIDI |
23 |
| 2016 | E350 4matic (wagon) | Auto 7-spd, 6 cyl, 3.5 L | 22 |
| 2016 | E400 | Auto 7-spd, 6 cyl, 3.0 L, Turbo | 23 |
| 2016 | E400 4matic | Auto 7-spd, 6 cyl, 3.0 L, Turbo | 22 |
| 2016 | E400 4matic Coupe | Auto 7-spd, 6 cyl, 3.0 L, Turbo | 23 |
| 2016 | E400 Convertible | Auto 7-spd, 6 cyl, 3.0 L, Turbo | 23 |
| 2016 | E400 Coupe | Auto 7-spd, 6 cyl, 3.0 L, Turbo | 23 |
| 2016 | E550 4matic | Auto 7-spd, 8 cyl, 4.7 L, Turbo | 21 |
| 2016 | E550 Convertible | Auto 7-spd, 8 cyl, 4.7 L, Turbo | 20 |
| 2016 | E550 Coupe | Auto 7-spd, 8 cyl, 4.7 L, Turbo | 21 |
| 2015 | E350 | Auto 7-spd, 6 cyl, 3.5 L, SIDI Auto 7-spd, 6 cyl, 3.5 L, SIDI; FFV |
23 |
| 2015 | E350 4matic | Auto 7-spd, 6 cyl, 3.5 L, SIDI Auto 7-spd, 6 cyl, 3.5 L, SIDI; FFV |
23 |
| 2015 | E350 4matic (wagon) | Auto 7-spd, 6 cyl, 3.5 L | 22 |
| 2015 | E350 Convertible | Auto 7-spd, 6 cyl, 3.5 L | 23 |
| 2015 | E350 Coupe | Auto 7-spd, 6 cyl, 3.5 L | 22 |
| 2015 | E400 | Auto 7-spd, 6 cyl, 3.0 L, Turbo | 23 |
| 2015 | E400 4matic | Auto 7-spd, 6 cyl, 3.0 L, Turbo | 22 |
| 2015 | E400 4matic (station wagon) | Auto 7-spd, 6 cyl, 3.0 L, Turbo | 22 |
| 2015 | E400 4matic Coupe | Auto 7-spd, 6 cyl, 3.0 L, Turbo | 23 |
| 2015 | E400 Convertible | Auto 7-spd, 6 cyl, 3.0 L, Turbo | 23 |
| 2015 | E400 Coupe | Auto 7-spd, 6 cyl, 3.0 L, Turbo | 23 |
| 2015 | E400 Hybrid | Auto 7-spd, 6 cyl, 3.5 L | 25 |
| 2015 | E550 Convertible | Auto 7-spd, 8 cyl, 4.7 L, Turbo | 20 |
| 2015 | E550 Coupe | Auto 7-spd, 8 cyl, 4.7 L, Turbo | 21 |
| 2015 | E63 AMG 4matic | Auto 7-spd, 8 cyl, 5.5 L, Turbo | 19 |
| 2015 | E63 AMG S 4matic | Auto 7-spd, 8 cyl, 5.5 L, Turbo | 18 |
| 2015 | E63 AMG S 4matic (wagon) | Auto 7-spd, 8 cyl, 5.5 L, Turbo | 18 |
| 2014 | E350 | Auto 7-spd, 6 cyl, 3.5 L, SIDI; PZEV (SULEV) emissions Auto 7-spd, 6 cyl, 3.5 L, SIDI; FFV Auto 7-spd, 6 cyl, 3.5 L, SIDI; ULEV Emissions |
23–24 |
| 2014 | E350 4matic | Auto 7-spd, 6 cyl, 3.5 L, SIDI; FFV Auto 7-spd, 6 cyl, 3.5 L, SIDI Auto 7-spd, 6 cyl, 3.5 L, SIDI; PZEV (SULEV) emissions |
22–23 |
| 2014 | E350 4matic (wagon) | Auto 7-spd, 6 cyl, 3.5 L | 22 |
| 2014 | E350 4matic Coupe | Auto 7-spd, 6 cyl, 3.5 L, SIDI; PZEV (SULEV) emissions Auto 7-spd, 6 cyl, 3.5 L, SIDI; FFV Auto 7-spd, 6 cyl, 3.5 L |
23 |
| 2014 | E350 Convertible | Auto 7-spd, 6 cyl, 3.5 L, SIDI; FFV Auto 7-spd, 6 cyl, 3.5 L, SIDI |
22–23 |
| 2014 | E350 Coupe | Auto 7-spd, 6 cyl, 3.5 L, SIDI; PZEV (SULEV) emissions Auto 7-spd, 6 cyl, 3.5 L, SIDI; FFV Auto 7-spd, 6 cyl, 3.5 L, SIDI |
23–24 |
| 2014 | E400 Hybrid | Auto 7-spd, 6 cyl, 3.5 L | 26 |
| 2014 | E550 4matic | Auto 7-spd, 8 cyl, 4.7 L, Turbo | 21 |
| 2014 | E550 Convertible | Auto 7-spd, 8 cyl, 4.7 L, Turbo | 20 |
| 2014 | E550 Coupe | Auto 7-spd, 8 cyl, 4.7 L, Turbo | 21 |
| 2014 | E63 AMG | Auto 7-spd, 8 cyl, 5.5 L, Turbo | 19 |
| 2014 | E63 AMG 4matic | Auto 7-spd, 8 cyl, 5.5 L, Turbo | 19 |
| 2014 | E63 AMG 4matic (wagon) | Auto 7-spd, 8 cyl, 5.5 L, Turbo | 17 |
| 2014 | E63 AMG S | Auto 7-spd, 8 cyl, 5.5 L, Turbo | 19 |
| 2014 | E63 AMG S 4matic | Auto 7-spd, 8 cyl, 5.5 L, Turbo | 18 |
| 2014 | E63 AMG S 4matic (wagon) | Auto 7-spd, 8 cyl, 5.5 L, Turbo | 18 |
| 2013 | E350 | Auto 7-spd, 6 cyl, 3.5 L, SIDI; PZEV(SULEV) emissions Auto 7-spd, 6 cyl, 3.5 L, SIDI Auto 7-spd, 6 cyl, 3.5 L, SIDI; FFV |
23 |
| 2013 | E350 4Matic | Auto 7-spd, 6 cyl, 3.5 L, SIDI; FFV | 22 |
| 2013 | E350 4matic | Auto 7-spd, 6 cyl, 3.5 L, SIDI; PZEV(SULEV) emissions Auto 7-spd, 6 cyl, 3.5 L, SIDI |
22 |
| 2013 | E350 4matic (wagon) | Auto 7-spd, 6 cyl, 3.5 L | 22 |
| 2013 | E350 4matic Coupe | Auto 7-spd, 6 cyl, 3.5 L, SIDI; PZEV(SULEV) emissions Auto 7-spd, 6 cyl, 3.5 L, SIDI; FFV Auto 7-spd, 6 cyl, 3.5 L, SIDI |
22 |
| 2013 | E350 Convertible | Auto 7-spd, 6 cyl, 3.5 L, SIDI; FFV Auto 7-spd, 6 cyl, 3.5 L, SIDI |
22 |
| 2013 | E350 Coupe | Auto 7-spd, 6 cyl, 3.5 L, SIDI; PZEV(SULEV) emissions Auto 7-spd, 6 cyl, 3.5 L, SIDI; FFV Auto 7-spd, 6 cyl, 3.5 L, SIDI |
23 |
| 2013 | E400 Hybrid | Auto 7-spd, 6 cyl, 3.5 L | 26 |
| 2013 | E550 4matic | Auto 7-spd, 8 cyl, 4.7 L, Turbo | 20 |
| 2013 | E550 Convertible | Auto 7-spd, 8 cyl, 4.7 L, Turbo | 19 |
| 2013 | E550 Coupe | Auto 7-spd, 8 cyl, 4.7 L, Turbo | 21 |
| 2013 | E63 AMG | Auto 7-spd, 8 cyl, 5.5 L, Turbo | 19 |
| 2013 | E63 AMG (wagon) | Auto 7-spd, 8 cyl, 5.5 L, Turbo | 18 |
| 2012 | E350 | Auto 7-spd, 6 cyl, 3.5 L | 23 |
| 2012 | E350 4matic | Auto 7-spd, 6 cyl, 3.5 L | 22 |
| 2012 | E350 4matic (wagon) | Auto 7-spd, 6 cyl, 3.5 L | 22 |
| 2012 | E350 4matic Coupe | Auto 7-spd, 6 cyl, 3.5 L, SIDI Auto 7-spd, 6 cyl, 3.5 L, SIDI; FFV |
22 |
| 2012 | E350 Convertible | Auto 7-spd, 6 cyl, 3.5 L, SIDI Auto 7-spd, 6 cyl, 3.5 L, SIDI; FFV |
22 |
| 2012 | E350 Coupe | Auto 7-spd, 6 cyl, 3.5 L, SIDI; FFV Auto 7-spd, 6 cyl, 3.5 L, SIDI |
22–23 |
| 2012 | E550 4matic | Auto 7-spd, 8 cyl, 4.7 L, Turbo | 20 |
| 2012 | E550 Convertible | Auto 7-spd, 8 cyl, 4.7 L, Turbo | 19 |
| 2012 | E550 Coupe | Auto 7-spd, 8 cyl, 4.7 L, Turbo | 21 |
| 2012 | E63 AMG | Auto 7-spd, 8 cyl, 5.5 L, Turbo | 19 |
| 2012 | E63 AMG (wagon) | Auto 7-spd, 8 cyl, 5.5 L, Turbo | 18 |
| 2011 | E350 | Auto 7-spd, 6 cyl, 3.5 L | 20 |
| 2011 | E350 4matic | Auto 7-spd, 6 cyl, 3.5 L | 19 |
| 2011 | E350 4matic (wagon) | Auto 7-spd, 6 cyl, 3.5 L | 19 |
| 2011 | E350 Convertible | Auto 7-spd, 6 cyl, 3.5 L | 20 |
| 2011 | E350 Coupe | Auto 7-spd, 6 cyl, 3.5 L | 20 |
| 2011 | E550 | Auto 7-spd, 8 cyl, 5.5 L | 18 |
| 2011 | E550 4matic | Auto 7-spd, 8 cyl, 5.5 L | 18 |
| 2011 | E550 Convertible | Auto 7-spd, 8 cyl, 5.5 L | 17 |
| 2011 | E550 Coupe | Auto 7-spd, 8 cyl, 5.5 L | 18 |
| 2011 | E63 AMG | Auto 7-spd, 8 cyl, 6.2 L | 15 |
| 2010 | E350 | Auto 7-spd, 6 cyl, 3.5 L | 21 |
| 2010 | E350 4matic | Auto 7-spd, 6 cyl, 3.5 L | 19 |
| 2010 | E350 Coupe | Auto 7-spd, 6 cyl, 3.5 L | 20 |
| 2010 | E550 | Auto 7-spd, 8 cyl, 5.5 L | 18 |
| 2010 | E550 4matic | Auto 7-spd, 8 cyl, 5.5 L | 18 |
| 2010 | E550 Coupe | Auto 7-spd, 8 cyl, 5.5 L | 18 |
| 2010 | E63 AMG | Auto 7-spd, 8 cyl, 6.3 L | 15 |
Source: fueleconomy.gov.